In this thought-provoking post, Nik Zeps (a consultant with AHRECS and a partner at Chrysalis) discusses the serious harm (in terms of reputation and career, as well as lost useful lines of inquiry) when there are complaints that allege ethical problems with clinical research.
These relate to situations where the clinical research is evaluating different kinds of intervention, where the evidence for the ‘accepted’ treatment might not be clear.
A misunderstanding of such research designs and a visceral reaction to apparent breaches aren’t helpful.
When such allegations are made, the researchers are rarely afforded an opportunity to respond and explain. If they were, one assumes that the manner could be easily cleared up.
We are embarrassed to admit in our own reporting of the cited case we really didn’t grasp the realities of what occurred or called out the very emotive reaction.
Regulation of human epigenetic editing: ensuring international frameworks for governing Human Genome Editing don’t impede vital medical research
In this thoughtful post, Nik Zeps reflects on human genome manipulation in medical research, the ethical guidance in Australia and internationally.
He discusses CRISPR and the furore in 2018 around the ‘genetically modified babies’ in China.
Nik then discusses the degree to which the COVID-19 pandemic has pushed discussions about human genetic manipulation off the media radar.
Nevertheless, there have been important international discussions about the topic, including a new WHO Framework. This topic was recently discussed in a paper by Zeps, Lysaght et al. 2021.
The situation might position the WHO as a major player in the international discussion about human genetic manipulation.
Embedding clinical research as part of routine healthcare: Managing the potential for competing interests. (UPDATED).
Nik Zeps AHRECS Consultant Clinical trials are widely accepted as the best method for understanding whether any particular medical
Nik Zeps and Tanya Symons AHRECS Consultant Breakthroughs in medicine often highlight the existing limitations of the frameworks established to
Nik Zeps AHRECS Consultant Clinical trials have enormous value to society as they provide the most robust means of working
After a paper has been through peer review and has been published it is the obligation of the scientific community
The Australian Code for the Responsible Conduct of Research 2007 (the Code) is Australia’s
January’s Methods Minutes, a monthly newsletter produced by Sage Publishing, is a special issue
But they shouldn’t equate to abridged consideration Dr Gary Allen | AHRECS senior consultant |
A Note on the Importance of Sensitising the Novice Researcher to the Realities of Ethics in Practice
Discussions of research ethics have begun to centre increasingly on how research guidelines translate