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ResourcesHuman Research EthicsA fascinating history of clinical trials from their beginnings in Babylon – Medium (Prof. Adrian Esterman | April 2020)

Australasian Human Research Ethics Consultancy Services Pty Ltd (AHRECS)

A fascinating history of clinical trials from their beginnings in Babylon – Medium (Prof. Adrian Esterman | April 2020)

 


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Clinical trials are required to test treatments for COVID-19. Take a quick trip over 2,000 years and discover how our current understanding of clinical trials was formed.

Clinical trials
Clinical trials are currently being undertaken to test treatments and vaccines for COVID-19. There are many different types of clinical trial design, from a simple before and after (measure something in patients, do an intervention like giving them a drug, then measure them again), to a randomized controlled trial, the gold standard of all clinical trial designs.

Planning to give a talk about clinical trials and want to give it some historical context?  This is a great resource to use.

Here is a light-hearted history of how clinical trials developed over the last two thousand years, including the first recorded instances of control groups, the use of placebos and randomization. It will give you a better understanding of how clinical trials are designed.
600 BC Daniel and his kosher diet.
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Surprisingly, the first ever clinical trial is found in the Bible in Book one of Daniel and took place in Babylon. In 600 BC, some captive children of the Israeli royal family and nobility were taken into the King Nebuchadnezzar’s service in Babylon — among them were Daniel and three friends. Supposedly, these were golden young men — physically perfect, handsome, intelligent, knowledgeable and well qualified to serve in the king’s palace.

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