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Australasian Human Research Ethics Consultancy Services Pty Ltd (AHRECS)

Paper submitted for publication without consent or knowledge of co-authors (COPE Case Study)0

Posted by Admin in on February 16, 2019
 

An article was submitted by corresponding author (CA) on 19 December 2011. After several revisions the article was accepted for publication on 23 March 2012. The article was published online 8 May 2012.

At the time of submission, CA was a PhD student at a research centre (X).

On 21 November 2012, co-author A (also head of the research group) contacted the publisher and editor-in-chief of journal A with a request to retract the published article claiming the following:

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Also  available as an audio file

Wake-up call from Hong Kong – Science (Victor J. Dzau, et al | December 2018)0

Posted by Admin in on February 12, 2019
 

The Second International Summit on Human Genome Editing, held in Hong Kong last month, was rocked by the revelation from a researcher from Shenzhen that twins were born whose healthy embryonic genomes had been edited to confer resistance to HIV. Despite widespread condemnation by the summit organizing committee, world scientific academies, and prominent scientific leaders that such research was “deeply disturbing” and “irresponsible,” and the launch of an investigation in China into the researcher’s actions, it is apparent that the ability to use CRISPR-Cas9 to edit the human genome has outpaced nascent efforts by the scientific and medical communities to confront the complex ethical and governance issues that they raise. The current guidelines and principles on human germline genome editing are based on sound scientific and ethical principles. However, this case highlights the urgent need to accelerate efforts to reach international agreement upon more specific criteria and standards that have to be met before human germline editing would be deemed permissible.

“We need…broad agreement on…criteria for human germline genome editing research…”

Together, we call upon international academies to quickly convene international experts and stakeholders to produce an expedited report that will inform the development of these criteria and standards to which all genome editing in human embryos for reproductive purposes must conform, and to engage scientific bodies around the world in this effort. The United States National Academies are willing to lead in this endeavor. Academies are well-positioned to convene needed international expertise and to help foster broad scientific consensus on the responsible pursuit of human genome editing research and clinical applications. We strongly believe that international consensus on such standards is important to avoid the potential for researchers to rationalize the justification or seek out convenient locales for conducting dangerous and unethical experimentation. The establishment of international scientific standards is not intended to substitute for national regulation but could inform such regulation.

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CRISPR-baby scientist fired by university – Nature (David Cyranoski | January 2019)0

Posted by Admin in on February 11, 2019
 

Investigation by Chinese authorities finds He Jiankui broke national regulations in his controversial work on gene-edited babies

The scientist who announced last year that he had produced the world’s first gene-edited babies has been fired by his university.

The decision, announced on 21 January by the Southern University of Science and Technology in Shenzhen, in China’s Guandong province, follows an investigation into He Jiankui’s work by provincial health authorities.

A probe by the Guangdong health ministry found that He broke national regulations against using gene-editing for reproductive purposes, Chinese state media agency Xinhua reported on 21 January.

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Scientist Who Used Gene Editing On Human Embryos Likely To Face Criminal Charges In China – KHN (January 2019)0

Posted by Admin in on February 11, 2019
 

China acknowledged the births and the fate of He Jiankui for the first time Monday. The Chinese ministry said it “resolutely opposed He’s work,” but the global science community argues He’s case underscores China’s lack of updated laws governing genetic research.

The New York Times: Scientist Who Edited Babies’ Genes Is Likely To Face Charges In China
A Chinese scientist who claimed to have created the world’s first genetically edited babies “seriously violated” state regulations, according to the results of an initial government investigation reported on Monday by Chinese state media. The investigators’ findings indicate that the scientist, He Jiankui, and his collaborators are likely to face criminal charges. (Ramzy and Wee, 1/21)

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