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Australasian Human Research Ethics Consultancy Services Pty Ltd (AHRECS)

Investigation into motives behind science misconduct – University World News (Suvendrini Kakuchi | August 2017)0

Posted by Admin in on October 20, 2017

Experts often point to the link between embarrassing retractions and tough pressure on academics to produce result-oriented investigations, but recent scandals have raised concerns of a more widespread culture of pressuring subordinates and other issues that lead to misconduct.

A brief review of responses to major research misconduct cases in Japan

The University of Tokyo, the country’s most prestigious research institution, this month revealed the results of its year-long investigation into data falsification involving five papers supervised and published by the university’s Institute of Molecular and Cellular Biosciences between 2008 and 2015. The scandal rocked the country’s scientific community last year.

It showed that rather than being isolated cases, intentional enhancement of images was common in that lab. The supervisor, a renowned Japanese cell biologist, Professor Yoshinori Watanabe, was identified as being mainly responsible for putting pressure on the co-author, his subordinate.

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Evidence based medicine manifesto for better healthcare – The BMJ (Carl Heneghan et al | June 2017)0

Posted by Admin in on October 11, 2017

A response to systematic bias, wastage, error, and fraud in research underpinning patient care

Another item bemoaning the impact of poor research on clinical practice but it also points to an initiative to address this.

Informed decision making requires clinicians and patients to identify and integrate relevant evidence. But with the questionable integrity of much of today’s evidence, the lack of research answering questions that matter to patients, and the lack of evidence to inform shared decision how are they expected to do this?
Too many research studies are poorly designed or executed. Too much of the resulting research evidence is withheld or disseminated piecemeal.1 As the volume of clinical research activity has grown2 the quality of evidence has often worsened,3 which has compromised the ability of all health professionals to provide affordable, effective, high value care for patients.”

Read the rest of this editorial and listen to a 41 minute discussion

Experiments in Judaism: Jewish Sources, Ethics, and Research with Human Subjects (Books: Alyssa Henning | 2015)0

Posted by Admin in on October 8, 2017

Henning explores the value of drawing on religious ethical traditions, in this case Judaism, as a source for challenging the limits of contemporary research ethics discourses. Her thesis offers an analysis of the scandal in 1963 at the Jewish Chronic Disease Hospital in Brooklyn when Dr Southam injected live, cultured cancer cells into 22 elderly patients to monitor their immune responses. She also explores the discourse of duty as a counter to the language of rights and liabilities.

Henning, Alyssa Anne (2015) Experiments in Judaism: Jewish Sources, Ethics, and Research with Human Subjects. Northwestern University, ProQuest Dissertations Publishing.

Also see
28/12/2013 – NYC’s forgotten cancer scandal – New York Post
Read the original news story from 1964

Fertility docs said their study didn’t need ethics review. An investigation said they were wrong – Retraction Watch (Andrew P. Han | September 2017)0

Posted by Admin in on October 5, 2017

A journal is retracting a paper on the relative merits of one fertility procedure compared to another because the study never received ethical review or approval.

Another ‘good’ example of failure to obtain ethical clearance becoming a research integrity matter.

In the paper, “Intracytoplasmic morphologically selected sperm injection versus conventional intracytoplasmic sperm injection: a randomized controlled trial,” originally published Aug. 27, 2015 in Reproductive Biology and Endocrinology, the authors wrote:

……“The Local Ethical Committee approval was not required because the procedure was commonly employed in the clinical practice.

Read the rest of this discussion piece