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He Jiankui’s Germline Editing Ethics Article Retracted by The CRISPR Journal – GEN (Julianna LeMieux – February 2019)0

Posted by Admin in on March 2, 2019

Failure to disclose conflicts of interest was “unacceptable”

Twelve weeks after publishing a perspective on the ethics of gene editing by He Jiankui, PhD, the scientist reportedly responsible for the first gene-edited humans, the editors of The CRISPR Journal have decided to retract the article, GEN can exclusively report.

This isn’t the only bewildering facet of the CRISPR Babies’ story, but it surely comes close to being the strangest.

In late November, the shocking news of the genetically edited twin girls broke out on the eve of the second international Human Genome Editing Summit in Hong Kong. The creation of germline-edited humans was unprecedented and not something that the scientific community had prepared for.

Most of the attention focused on the actions of 34-year-old He, formerly a professor at the Southern University of Science and Technology (SUSTech) in Shenzhen. He’s decision to ignore advice from prominent members of the scientific community and serious questions over the technical and ethical procedures prompted an immediate investigation by Chinese authorities while he was held under house arrest, culminating in his dismissal by SUSTech last month.|

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Will the world embrace Plan S, the radical proposal to mandate open access to science papers? – Science (Tania Rabesandratana | January 2019)0

Posted by Admin in on February 24, 2019

How far will Plan S spread?

Since the September 2018 launch of the Europe-backed program to mandate immediate open access (OA) to scientific literature, 16 funders in 13 countries have signed on. That’s still far shy of Plan S’s ambition: to convince the world’s major research funders to require immediate OA to all published papers stemming from their grants. Whether it will reach that goal depends in part on details that remain to be settled, including a cap on the author charges that funders will pay for OA publication. But the plan has gained momentum: In December 2018, China stunned many by expressing strong support for Plan S. This month, a national funding agency in Africa is expected to join, possibly followed by a second U.S. funder. Others around the world are considering whether to sign on.

Plan S, scheduled to take effect on 1 January 2020, has drawn support from many scientists, who welcome a shake-up of a publishing system that can generate large profits while keeping taxpayer-funded research results behind paywalls. But publishers (including AAAS, which publishes Science) are concerned, and some scientists worry that Plan S could restrict their choices.

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(JAP) Japanese stem cell fraud leads to a new retraction – Retraction Watch (Adam Marcus | January 2019)0

Posted by Admin in on February 23, 2019

Last March, we reported on the retraction of a 2017 paper in Stem Cell Reports by Kohei Yamamizu and colleagues for widespread fabrication of figures. Turns out the problems were at least five years older than that.

Yamamizu had received a pink slip from his institution, the Center for iPS Cell Research and Application (CiRA), which had put the blame for the misconduct squarely on his shoulders. (The director of the institute, Nobel winner Shinya Yamanaka, also took some of the blame in a public statement in which he said he bore “a strong responsibility for not having prevented research misconduct at our institute.”)

Yamamizu has a new retraction, but this time’s a bit different. Here’s the notice for the paper, “Protein Kinase A Determines Timing of Early Differentiation through Epigenetic Regulation with G9,” which appeared in Cell Stem Cell in June 2012 (Yamanaka was not a co-author on either study).  Although the statement acknowledges the internal investigation, it doesn’t mention misconduct or name Yamamizu:

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Paper submitted for publication without consent or knowledge of co-authors (COPE Case Study)0

Posted by Admin in on February 16, 2019

An article was submitted by corresponding author (CA) on 19 December 2011. After several revisions the article was accepted for publication on 23 March 2012. The article was published online 8 May 2012.

At the time of submission, CA was a PhD student at a research centre (X).

On 21 November 2012, co-author A (also head of the research group) contacted the publisher and editor-in-chief of journal A with a request to retract the published article claiming the following:

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